Yes. Airlines may verify ESTA before flight boarding for travelers going to the United States.
Travelers under the Visa Waiver Program must have an approved ESTA before boarding a U.S.-bound flight, so airlines may check ESTA status during check-in or the boarding process.
Therefore, if you plan to take a flight to the United States, it is recommended to check your ESTA approval status before going to the airport.
If you are preparing for travel to the United States, please make sure to apply for ESTA before departure.